Listeria monocytogenes endophthalmitis following keratoconjunctivitis

Samir S. Shoughy, Khalid F. Tabbara

Research output: Contribution to journalArticlepeer-review

Abstract

Endophthalmitis due to endogenous or exogenous bacteria is a rare infection of the eye. We report a case of endophthalmitis following Listeria monocytogenes keratoconjunctivitis in a 27-year-old healthy white male presenting with hand motion visual acuity, right eye mucopurulent conjunctivitis, elevated intraocular pressure, and pigmented hypopyon 6 months post-keratectomy. The conjunctivitis was unresponsive to a 5-day course of topical tobramycin eye drops, and the patient developed keratitis with pain that progressed to endophthalmitis after 21 days. Diagnostic B-scan revealed vitreous exudates. Intraocular fluid specimen showed Gram-positive organisms and the aqueous culture grew penicillin-/aminoglycoside-sensitive L. monocytogenes. The patient was given intravitreal and systemic vancomycin and ceftazidime. The eye was unresponsive to intravenous penicillin and gentamicin; the anterior chamber progressively flattened and developed phthisis bulbi. L. monocytogenes keratoconjunctivitis may lead to bacterial endophthalmitis. Prompt culture and early antibiotic therapy are recommended.

Original languageEnglish (US)
Pages (from-to)301-304
Number of pages4
JournalClinical Ophthalmology
Volume8
DOIs
StatePublished - Jan 24 2014

Keywords

  • Conjunctivitis
  • Endophthalmitis
  • L. monocytogenes

ASJC Scopus subject areas

  • Ophthalmology

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