Lissamine Green Staining in the Clinical Diagnosis of Xerophthalmia

Nani Emran, Alfred Sommer

Research output: Contribution to journalArticlepeer-review

Abstract

Lissamine green staining of the conjunctiva, a new and widely heralded aid for diagnosing early xerophthalmia, was found to be a reasonably specific but inadequately sensitive test for practical use. While 82% of clinically normal children failed to show staining, so did 57% with night blindness, 29% with vitamin A responsive Bitot's spots, and, most significantly, 26% with severe, vitamin A related corneal involvement. The test also failed to distinguish vitamin A responsive “Bitot's spots” from nonresponsive ones.

Original languageEnglish (US)
Pages (from-to)2333-2335
Number of pages3
JournalArchives of ophthalmology
Volume97
Issue number12
DOIs
StatePublished - Dec 1979

ASJC Scopus subject areas

  • Ophthalmology

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