Liquid infrared atmospheric pressure matrix-assisted laser desorption/ionization ion trap mass spectrometry of sialylated carbohydrates

Christopher E. Von Seggern, Susanne C. Moyer, Robert J. Cotter

Research output: Contribution to journalArticlepeer-review

Abstract

A 2.94-μm Er:YAG laser for IR atmospheric pressure matrix-assisted laser desorption/ionization on an ion trap mass spectrometer is used for the analysis of sialylated oligosaccharides. This approach provided the opportunity to utilize liquid matrixes and is effective in determining structural features - sequence, branching, and linkage - of intact, fully sialylated molecular species.

Original languageEnglish (US)
Pages (from-to)3212-3218
Number of pages7
JournalAnalytical chemistry
Volume75
Issue number13
DOIs
StatePublished - Jul 1 2003

ASJC Scopus subject areas

  • Analytical Chemistry

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