Linking cilia to Wnts

Gregory G. Germino

Research output: Contribution to journalArticlepeer-review

Abstract

Inversin is a component of a poorly understood cilia-based mechanism responsible for specifying the left-right axis during development and for maintaining normal kidney architecture throughout life. A new study now suggests that inversin might act as a flow-regulated molecular switch between canonical and noncanonical Wnt pathways, providing insights into the mechanisms underlying cilia-based signaling processes.

Original languageEnglish (US)
Pages (from-to)455-457
Number of pages3
JournalNature Genetics
Volume37
Issue number5
DOIs
StatePublished - May 2005

ASJC Scopus subject areas

  • Genetics(clinical)
  • Genetics

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