Linkage analysis of genetic disorders.

E. W. Taylor, J. Xu, E. W. Jabs, D. A. Meyers

Research output: Contribution to journalArticle

Abstract

Basic principles and methods of genetic analysis were covered in this chapter. The approaches of linkage analysis for Mendelian or complex disorders can be summarized in the following flowchart (Fig. 2). It is important that the clinical, analytical, and molecular investigators be involved in all steps in the process. Mapping genes for complex disorders is often more difficult than mapping genes for Mendelian disorders, but both may prove to be very important in understanding disease processes and designing new treatments. Practical use of computer programs available for genetic analysis is detailed elsewhere (24).

Original languageEnglish (US)
Pages (from-to)11-25
Number of pages15
JournalMethods in molecular biology (Clifton, N.J.)
Volume68
StatePublished - 1997

Fingerprint

Inborn Genetic Diseases
Chromosome Mapping
Software Design
Software
Research Personnel

ASJC Scopus subject areas

  • Molecular Biology
  • Genetics

Cite this

Taylor, E. W., Xu, J., Jabs, E. W., & Meyers, D. A. (1997). Linkage analysis of genetic disorders. Methods in molecular biology (Clifton, N.J.), 68, 11-25.

Linkage analysis of genetic disorders. / Taylor, E. W.; Xu, J.; Jabs, E. W.; Meyers, D. A.

In: Methods in molecular biology (Clifton, N.J.), Vol. 68, 1997, p. 11-25.

Research output: Contribution to journalArticle

Taylor, EW, Xu, J, Jabs, EW & Meyers, DA 1997, 'Linkage analysis of genetic disorders.', Methods in molecular biology (Clifton, N.J.), vol. 68, pp. 11-25.
Taylor, E. W. ; Xu, J. ; Jabs, E. W. ; Meyers, D. A. / Linkage analysis of genetic disorders. In: Methods in molecular biology (Clifton, N.J.). 1997 ; Vol. 68. pp. 11-25.
@article{2c27651cb7f643b2bad835a061ed5817,
title = "Linkage analysis of genetic disorders.",
abstract = "Basic principles and methods of genetic analysis were covered in this chapter. The approaches of linkage analysis for Mendelian or complex disorders can be summarized in the following flowchart (Fig. 2). It is important that the clinical, analytical, and molecular investigators be involved in all steps in the process. Mapping genes for complex disorders is often more difficult than mapping genes for Mendelian disorders, but both may prove to be very important in understanding disease processes and designing new treatments. Practical use of computer programs available for genetic analysis is detailed elsewhere (24).",
author = "Taylor, {E. W.} and J. Xu and Jabs, {E. W.} and Meyers, {D. A.}",
year = "1997",
language = "English (US)",
volume = "68",
pages = "11--25",
journal = "Methods in Molecular Biology",
issn = "1064-3745",
publisher = "Humana Press",

}

TY - JOUR

T1 - Linkage analysis of genetic disorders.

AU - Taylor, E. W.

AU - Xu, J.

AU - Jabs, E. W.

AU - Meyers, D. A.

PY - 1997

Y1 - 1997

N2 - Basic principles and methods of genetic analysis were covered in this chapter. The approaches of linkage analysis for Mendelian or complex disorders can be summarized in the following flowchart (Fig. 2). It is important that the clinical, analytical, and molecular investigators be involved in all steps in the process. Mapping genes for complex disorders is often more difficult than mapping genes for Mendelian disorders, but both may prove to be very important in understanding disease processes and designing new treatments. Practical use of computer programs available for genetic analysis is detailed elsewhere (24).

AB - Basic principles and methods of genetic analysis were covered in this chapter. The approaches of linkage analysis for Mendelian or complex disorders can be summarized in the following flowchart (Fig. 2). It is important that the clinical, analytical, and molecular investigators be involved in all steps in the process. Mapping genes for complex disorders is often more difficult than mapping genes for Mendelian disorders, but both may prove to be very important in understanding disease processes and designing new treatments. Practical use of computer programs available for genetic analysis is detailed elsewhere (24).

UR - http://www.scopus.com/inward/record.url?scp=0030637198&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0030637198&partnerID=8YFLogxK

M3 - Article

C2 - 9055247

AN - SCOPUS:0030637198

VL - 68

SP - 11

EP - 25

JO - Methods in Molecular Biology

JF - Methods in Molecular Biology

SN - 1064-3745

ER -