Limited angle dual modality breast imaging

Mitali J. Moré, Heng Li, Patricia J. Goodale, Yibin Zheng, Stan Majewski, Vladimir Popov, Benjamin Welch, Mark B. Williams

Research output: Contribution to journalArticle

Abstract

We are developing a dual modality breast scanner that can obtain x-ray transmission and gamma ray emission images in succession at multiple viewing angles with the breast held under mild compression. These views are reconstructed and fused to obtain three-dimensional images that combine structural and functional information. Here, we describe the dual modality system and present results of phantom experiments designed to test the system's ability to obtain fused volumetric dual modality data sets from a limited number of projections, acquired over a limited (less than 180 degrees) angular range. We also present initial results from phantom experiments conducted to optimize the acquisition geometry for gamma imaging. The optimization parameters include the total number of views and the angular range over which these views should be spread, while keeping the total number of detected counts fixed. We have found that in general, for a fixed number of views centered around the direction perpendicular to the direction of compression, in-plane contrast and SNR are improved as the angular range of the views is decreased. The improvement in contrast and SNR with decreasing angular range is much greater for deeper lesions and for a smaller number of views. However, the z-resolution of the lesion is significantly reduced with decreasing angular range. Finally, we present results from limited angle tomography scans using a system with dual, opposing heads.

Original languageEnglish (US)
Pages (from-to)504-513
Number of pages10
JournalIEEE Transactions on Nuclear Science
Volume54
Issue number3
DOIs
StatePublished - Jun 1 2007
Externally publishedYes

Keywords

  • Digital mammography
  • Seintimammography
  • Tomography

ASJC Scopus subject areas

  • Nuclear and High Energy Physics
  • Nuclear Energy and Engineering
  • Electrical and Electronic Engineering

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  • Cite this

    Moré, M. J., Li, H., Goodale, P. J., Zheng, Y., Majewski, S., Popov, V., Welch, B., & Williams, M. B. (2007). Limited angle dual modality breast imaging. IEEE Transactions on Nuclear Science, 54(3), 504-513. https://doi.org/10.1109/TNS.2007.897828