Limitations of Resting-State Functional MR Imaging in the Setting of Focal Brain Lesions

Shruti Agarwal; Haris I. Sair; Jay J. Pillai

doi:10.1016/j.nic.2017.06.004

Limitations of Resting-State Functional MR Imaging in the Setting of Focal Brain Lesions

Shruti Agarwal, Haris I. Sair, Jay J. Pillai

School of Medicine

Research output: Contribution to journal › Review article › peer-review

7 Scopus citations

Abstract

Methods of image acquisition and analysis for resting-state functional MR imaging (rsfMR imaging) are still evolving. Neurovascular uncoupling and susceptibility artifact are important confounds of rsfMR imaging in the setting of focal brain lesions such as brain tumors. This article reviews the detection of these confounds using rsfMR imaging metrics in the setting of focal brain lesions. In the near future, with the wide range of ongoing research in rsfMR imaging, these issues likely will be overcome and will open new windows into brain function and connectivity.

Original language	English (US)
Pages (from-to)	645-661
Number of pages	17
Journal	Neuroimaging Clinics of North America
Volume	27
Issue number	4
DOIs	https://doi.org/10.1016/j.nic.2017.06.004
State	Published - Nov 2017

Keywords

Motor activation
Neurovascular uncoupling
Presurgical mapping
Resting-state fMR imaging

ASJC Scopus subject areas

Radiology Nuclear Medicine and imaging
Clinical Neurology

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10.1016/j.nic.2017.06.004

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title = "Limitations of Resting-State Functional MR Imaging in the Setting of Focal Brain Lesions",

abstract = "Methods of image acquisition and analysis for resting-state functional MR imaging (rsfMR imaging) are still evolving. Neurovascular uncoupling and susceptibility artifact are important confounds of rsfMR imaging in the setting of focal brain lesions such as brain tumors. This article reviews the detection of these confounds using rsfMR imaging metrics in the setting of focal brain lesions. In the near future, with the wide range of ongoing research in rsfMR imaging, these issues likely will be overcome and will open new windows into brain function and connectivity.",

keywords = "Motor activation, Neurovascular uncoupling, Presurgical mapping, Resting-state fMR imaging",

author = "Shruti Agarwal and Sair, {Haris I.} and Pillai, {Jay J.}",

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AU - Agarwal, Shruti

AU - Sair, Haris I.

AU - Pillai, Jay J.

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Y1 - 2017/11

N2 - Methods of image acquisition and analysis for resting-state functional MR imaging (rsfMR imaging) are still evolving. Neurovascular uncoupling and susceptibility artifact are important confounds of rsfMR imaging in the setting of focal brain lesions such as brain tumors. This article reviews the detection of these confounds using rsfMR imaging metrics in the setting of focal brain lesions. In the near future, with the wide range of ongoing research in rsfMR imaging, these issues likely will be overcome and will open new windows into brain function and connectivity.

AB - Methods of image acquisition and analysis for resting-state functional MR imaging (rsfMR imaging) are still evolving. Neurovascular uncoupling and susceptibility artifact are important confounds of rsfMR imaging in the setting of focal brain lesions such as brain tumors. This article reviews the detection of these confounds using rsfMR imaging metrics in the setting of focal brain lesions. In the near future, with the wide range of ongoing research in rsfMR imaging, these issues likely will be overcome and will open new windows into brain function and connectivity.

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KW - Presurgical mapping

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Limitations of Resting-State Functional MR Imaging in the Setting of Focal Brain Lesions

Abstract

Keywords

ASJC Scopus subject areas

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