Radio-telemetry technique used to record electro - physiological signals in animals is broadly used in experimental studies. Using implantable probes, this technique can record electrocardiographic (ECG) signals without disturbing animal activities. In this study, we investigated the stability of heart rate variability (HRV) parameters computed from radio-telemetry ECG recordings in unrestrained rats. The experiment involved 4 normal rats in which ECGs were recorded during baseline conditions with and without drug-induced autonomie blockade. The study revealed that the stability of HRV estimators for both time and frequency domains analysis in unrestrained rats was highly dependent on the average heart rate (related to physical rats activity) as well as the length of the ECG recording.
ASJC Scopus subject areas
- Computer Science Applications
- Cardiology and Cardiovascular Medicine