Limitations and alternatives to endoscopic correction of vesicoureteral reflux with Polytef paste

Douglas A. Canning, John Phillip Gearhart

Research output: Contribution to journalArticle

Abstract

Despite increased use with encouraging success rates, endoscopic correction of vesicoureteral reflux in children has persistent limitations. While many patients may be managed with this technique, a few with complete ureteral duplication or paraureteral diverticulum will not be successfully corrected. Nevertheless, precise placement of the implant beneath the ureteral orifice has resulted in success even in patients with highgrade reflux, patients with neuropathic bladder and in patients who have failed previous ureteroneocystostomy. Concern remains regarding the safety of the injectable Teflon substance, which elicits a local and distant foreign-body granuloma response. This has been noted in animal models and in a few human patients. Alternative substances such as glutaraldehyde cross-linked collagen and transplanted autologous fat may eliminate concern regarding the safety of the implant while preserving the excellent results reported with injectable Teflon.

Original languageEnglish (US)
Pages (from-to)149-153
Number of pages5
JournalPediatric Surgery International
Volume4
Issue number3
DOIs
StatePublished - Apr 1989

Fingerprint

Vesico-Ureteral Reflux
Polytetrafluoroethylene
Ointments
Foreign-Body Granuloma
Safety
Neurogenic Urinary Bladder
Injections
Diverticulum
Animal Models
Fats

Keywords

  • Alternatives
  • Endoscopic correction
  • Limitations
  • Polytef paste
  • Vesicoureteral reflux

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

Cite this

Limitations and alternatives to endoscopic correction of vesicoureteral reflux with Polytef paste. / Canning, Douglas A.; Gearhart, John Phillip.

In: Pediatric Surgery International, Vol. 4, No. 3, 04.1989, p. 149-153.

Research output: Contribution to journalArticle

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