TY - JOUR
T1 - Limbic and new onset refractory tonic status epilepticus (NORSE) in anti-NMDAR encephalitis
AU - Kaplan, Peter W.
AU - Probasco, John
N1 - Publisher Copyright:
© 2017 International Federation of Clinical Neurophysiology
PY - 2017
Y1 - 2017
N2 - Aims: To present a case of anti-NMDA receptor encephalitis (anti-NMDAR) with new onset refractory non-convulsive status epilepticus (NORSE). Methods: Case report with clinical details, MRI, PET, and EEG illustrations. Results: New onset refractory status epilepticus (NORSE) may arise from anti-NMDAR, and offers diagnostic and treatment challenges for immuno-therapy and refractory status epilepticus. Non-convulsive status epilepticus with generalized fast activity, has not been reported in anti-NMDAR, in NORSE. Conclusions: A patient with anti-NMDAR and generalized status with stiffening, right focal weakness, high frequency alpha/beta on EEG, brain FDG-PET/CT changes in the left temporo-parietal regions and cerebellum was presented. We discuss the unique treatment challenges of anti-NMDAR. NORSE and generalized nonconvulsive status epilepticus.
AB - Aims: To present a case of anti-NMDA receptor encephalitis (anti-NMDAR) with new onset refractory non-convulsive status epilepticus (NORSE). Methods: Case report with clinical details, MRI, PET, and EEG illustrations. Results: New onset refractory status epilepticus (NORSE) may arise from anti-NMDAR, and offers diagnostic and treatment challenges for immuno-therapy and refractory status epilepticus. Non-convulsive status epilepticus with generalized fast activity, has not been reported in anti-NMDAR, in NORSE. Conclusions: A patient with anti-NMDAR and generalized status with stiffening, right focal weakness, high frequency alpha/beta on EEG, brain FDG-PET/CT changes in the left temporo-parietal regions and cerebellum was presented. We discuss the unique treatment challenges of anti-NMDAR. NORSE and generalized nonconvulsive status epilepticus.
KW - Anti-NMDAR
KW - Limbic encephalitis
KW - Limbic status epilepticus
KW - NORSE
KW - Tonic status epilepticus
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U2 - 10.1016/j.cnp.2017.06.003
DO - 10.1016/j.cnp.2017.06.003
M3 - Article
AN - SCOPUS:85044761104
SN - 2467-981X
VL - 2
SP - 140
EP - 143
JO - Clinical Neurophysiology Practice
JF - Clinical Neurophysiology Practice
ER -