Likelihood of reaching minimal clinically important difference in adult spinal deformity

A comparison of operative and nonoperative treatment

Shian Liu, Frank Schwab, Justin S. Smith, Eric Klineberg, Christopher P. Ames, Gregory Mundis, Richard Hostin, Khaled M Kebaish, Vedat Deviren, Munish Gupta, Oheneba Boachie-Adjei, Robert A. Hart, Shay Bess, Virginie Lafage

Research output: Contribution to journalArticle

Abstract

Background: Few studies have examined threshold improvements in health-related quality of life (HRQOL) by measuring minimal clinically important differences (MCIDs) in treatment of adult spinal deformity. We hypothesized that patients undergoing operative treatment would be more likely to achieve MCID threshold improvement compared with those receiving nonoperative care, although a subset of nonoperative patients may still reach threshold. Methods: We analyzed a multicenter, prospective, consecutive case series of 464 patients: 225 nonoperative and 239 operative. To be included in the study, patients had to have adult spinal deformity, be older than 18 years, and have both baseline and 1-year follow-up HRQOL measures (Oswestry Disability Index [ODI], Short Form-36 [SF-36] health survey, and Scoliosis Research Society-22 [SRS-22] questionnaire). We compared the percentages of patients achieving established MCID thresholds between operative and nonoperative groups using risk ratios (RR) with a 95% confidence interval (CI). Results: Compared to nonoperative patients, surgical patients demonstrated significant mean improvement (P

Original languageEnglish (US)
Pages (from-to)67-77
Number of pages11
JournalOchsner Journal
Volume14
Issue number1
StatePublished - 2014

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Therapeutics
Quality of Life
Scoliosis
Minimal Clinically Important Difference
Health Surveys
Odds Ratio
Confidence Intervals
Research
Surveys and Questionnaires

Keywords

  • Disability evaluation
  • Pain management
  • Quality of life
  • Spinal cord diseases
  • Surgical procedures-operative

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Liu, S., Schwab, F., Smith, J. S., Klineberg, E., Ames, C. P., Mundis, G., ... Lafage, V. (2014). Likelihood of reaching minimal clinically important difference in adult spinal deformity: A comparison of operative and nonoperative treatment. Ochsner Journal, 14(1), 67-77.

Likelihood of reaching minimal clinically important difference in adult spinal deformity : A comparison of operative and nonoperative treatment. / Liu, Shian; Schwab, Frank; Smith, Justin S.; Klineberg, Eric; Ames, Christopher P.; Mundis, Gregory; Hostin, Richard; Kebaish, Khaled M; Deviren, Vedat; Gupta, Munish; Boachie-Adjei, Oheneba; Hart, Robert A.; Bess, Shay; Lafage, Virginie.

In: Ochsner Journal, Vol. 14, No. 1, 2014, p. 67-77.

Research output: Contribution to journalArticle

Liu, S, Schwab, F, Smith, JS, Klineberg, E, Ames, CP, Mundis, G, Hostin, R, Kebaish, KM, Deviren, V, Gupta, M, Boachie-Adjei, O, Hart, RA, Bess, S & Lafage, V 2014, 'Likelihood of reaching minimal clinically important difference in adult spinal deformity: A comparison of operative and nonoperative treatment', Ochsner Journal, vol. 14, no. 1, pp. 67-77.
Liu, Shian ; Schwab, Frank ; Smith, Justin S. ; Klineberg, Eric ; Ames, Christopher P. ; Mundis, Gregory ; Hostin, Richard ; Kebaish, Khaled M ; Deviren, Vedat ; Gupta, Munish ; Boachie-Adjei, Oheneba ; Hart, Robert A. ; Bess, Shay ; Lafage, Virginie. / Likelihood of reaching minimal clinically important difference in adult spinal deformity : A comparison of operative and nonoperative treatment. In: Ochsner Journal. 2014 ; Vol. 14, No. 1. pp. 67-77.
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