Lifestyle interventions reduce coronary heart disease risk results from the premier trial

Research output: Contribution to journalArticle


Although trials of lifestyle interventions generally focus on cardiovascular disease risk factors rather than hard clinical outcomes, 10-year coronary heart disease (CHD) risk can be estimated from the Framingham risk equations. Our objectives were to study the effect of 2 multicomponent lifestyle interventions on estimated CHD risk relative to advice alone and to evaluate whether differences can be observed in the effects of the lifestyle interventions among subgroups defined by baseline variables.

Original languageEnglish (US)
Pages (from-to)2026-2031
Number of pages6
Issue number15
StatePublished - Apr 21 2009



  • Coronary disease
  • Lifestyle
  • Prevention
  • Risk factors

ASJC Scopus subject areas

  • Physiology (medical)
  • Cardiology and Cardiovascular Medicine

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