Life or death: Developing cortical interneurons make their own decision

Juan Song, Kimberly M. Christian, Guo Li Ming, Hongjun Song

Research output: Contribution to journalArticlepeer-review

Abstract

During nervous system development, programmed cell death is considered as an essential adaptive process. The mechanism by which the number of mature neurons is determined in the central nervous system is not well understood. In a recent Nature paper, Southwell et al (2012) demonstrate that cortical GABAergic interneuron cell death is intrinsically determined without the need to compete for extrinsic survival signals derived from other cell types.

Original languageEnglish (US)
Pages (from-to)4373-4374
Number of pages2
JournalThe EMBO journal
Volume31
Issue number23
DOIs
StatePublished - Nov 28 2012

ASJC Scopus subject areas

  • Molecular Biology
  • Biochemistry, Genetics and Molecular Biology(all)
  • Immunology and Microbiology(all)
  • Neuroscience(all)

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