Life or death: Developing cortical interneurons make their own decision

Juan Song; Kimberly M. Christian; Guo Li Ming; Hongjun Song

doi:10.1038/emboj.2012.290

Life or death: Developing cortical interneurons make their own decision

Juan Song, Kimberly M. Christian, Guo Li Ming, Hongjun Song

School of Medicine

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Abstract

During nervous system development, programmed cell death is considered as an essential adaptive process. The mechanism by which the number of mature neurons is determined in the central nervous system is not well understood. In a recent Nature paper, Southwell et al (2012) demonstrate that cortical GABAergic interneuron cell death is intrinsically determined without the need to compete for extrinsic survival signals derived from other cell types.

Original language	English (US)
Pages (from-to)	4373-4374
Number of pages	2
Journal	The EMBO journal
Volume	31
Issue number	23
DOIs	https://doi.org/10.1038/emboj.2012.290
State	Published - Nov 28 2012

ASJC Scopus subject areas

Molecular Biology
General Biochemistry, Genetics and Molecular Biology
General Immunology and Microbiology
General Neuroscience

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10.1038/emboj.2012.290

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abstract = "During nervous system development, programmed cell death is considered as an essential adaptive process. The mechanism by which the number of mature neurons is determined in the central nervous system is not well understood. In a recent Nature paper, Southwell et al (2012) demonstrate that cortical GABAergic interneuron cell death is intrinsically determined without the need to compete for extrinsic survival signals derived from other cell types.",

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Life or death: Developing cortical interneurons make their own decision

Abstract

ASJC Scopus subject areas

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