Life history: Mother-specific proteins that promote aging

Chuankai Zhou, Rong Li, Brian K. Kennedy

Research output: Contribution to journalShort surveypeer-review


A yeast mother cell progressively ages with each cell division and yet produces daughter cells that are largely rejuvenated, suggesting that mothers accumulate aging factors. Two current studies address this issue by identifying mother-specific long-lived proteins and, in the case of Pma1, evidence that asymmetric distribution drives mother cell aging.

Original languageEnglish (US)
Pages (from-to)R1162-R1164
JournalCurrent Biology
Issue number24
StatePublished - Dec 15 2014
Externally publishedYes

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Agricultural and Biological Sciences(all)


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