A yeast mother cell progressively ages with each cell division and yet produces daughter cells that are largely rejuvenated, suggesting that mothers accumulate aging factors. Two current studies address this issue by identifying mother-specific long-lived proteins and, in the case of Pma1, evidence that asymmetric distribution drives mother cell aging.
ASJC Scopus subject areas
- Biochemistry, Genetics and Molecular Biology(all)
- Agricultural and Biological Sciences(all)