TY - JOUR
T1 - Life course socioeconomic position and subcl inical disease
T2 - The jackson heart study
AU - Deere, Bradley
AU - Griswold, Michael
AU - Lirette, Seth
AU - Fox, Ervin
AU - Sims, Mario
N1 - Funding Information:
The authors thank the Jackson Heart Study team (University of Mississippi Medical Center, Jackson State University and Tougaloo College) and participants for their long-term commitment that continues to improve our understanding of the epidemiology of cardiovascular and other chronic diseases. The authors take responsibility for the contents of the article and have no disclosures. Funding Sources: The JHS is supported by contracts HHSN268201300046C, HHSN268201300047C, HHSN268201300048C, HHSN268201300049C, HHSN268201300050C from the National Heart, Lung, and Blood Institute (NHLBI) and the National Institute on Minority Health and Health Disparities (NIMHD). The senior author is supported by the grants P60MD002249 and U54MD008176 from the NIMHD.
PY - 2016/6/1
Y1 - 2016/6/1
N2 - Objectives: African Americans experience higher rates of cardiovascular disease (CVD) and lower childhood and adult socioeconomic position (SEP). Research that examines the associations of multiple measures of SEP with subclinical CVD markers among African Americans is limited. Methods: Data from the Jackson Heart Study (JHS) were used to examine crosssectional associations of childhood SEP and adult SEP with subclinical markers among 4,756 African American participants (mean age 54, 64% female), adjusting for age, health behaviors and CVD risk factors. Subclinical markers included prevalent left ventricular hypertrophy (LVH), peripheral artery disease (PAD), coronary artery calcification (CAC), and carotid intima-media thickness (CIMT). Results: The prevalence of LVH, PAD and CAC was 7%, 6% and 45%, respectively. The mean CIMT was .72 ± .17 mm. In fully-adjusted models, having a college education was inversely associated with PAD (OR, .27; 95% CI .13,.56) and CIMT (?=-29.7, P<.01). Income was inversely associated with LVH after adjustment for health behaviors (OR, .49 95% CI .25,.96), though associations attenuated in the fully-adjusted model. Measures of childhood SEP (material resources and mother's education) were not consistently associated with subclinical disease measures other than a positive association between material resources and CIMT. Conclusions: Subclinical disease markers were patterned by adult SEP measures among African Americans.
AB - Objectives: African Americans experience higher rates of cardiovascular disease (CVD) and lower childhood and adult socioeconomic position (SEP). Research that examines the associations of multiple measures of SEP with subclinical CVD markers among African Americans is limited. Methods: Data from the Jackson Heart Study (JHS) were used to examine crosssectional associations of childhood SEP and adult SEP with subclinical markers among 4,756 African American participants (mean age 54, 64% female), adjusting for age, health behaviors and CVD risk factors. Subclinical markers included prevalent left ventricular hypertrophy (LVH), peripheral artery disease (PAD), coronary artery calcification (CAC), and carotid intima-media thickness (CIMT). Results: The prevalence of LVH, PAD and CAC was 7%, 6% and 45%, respectively. The mean CIMT was .72 ± .17 mm. In fully-adjusted models, having a college education was inversely associated with PAD (OR, .27; 95% CI .13,.56) and CIMT (?=-29.7, P<.01). Income was inversely associated with LVH after adjustment for health behaviors (OR, .49 95% CI .25,.96), though associations attenuated in the fully-adjusted model. Measures of childhood SEP (material resources and mother's education) were not consistently associated with subclinical disease measures other than a positive association between material resources and CIMT. Conclusions: Subclinical disease markers were patterned by adult SEP measures among African Americans.
KW - African American
KW - Socioeconomic Position
KW - Subclinical Cardiovascular Disease
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U2 - 10.18865/ed.26.3.355
DO - 10.18865/ed.26.3.355
M3 - Article
C2 - 27440975
AN - SCOPUS:84979695336
SN - 1049-510X
VL - 26
SP - 355
EP - 362
JO - Ethnicity and Disease
JF - Ethnicity and Disease
IS - 3
ER -