Abstract
Levetiracetam (LEV) is effective for treating localisation-related epilepsy, but it is uncertain whether it is effective for treating idiopathic generalised epilepsy. We compared 12-week baseline and LEV treatment periods for patients with generalised seizure types - myoclonic, tonic-clonic and absence seizures - who had failed other anticonvulsants. The majority of 55 patients (76%) had >50% seizure reduction with LEV therapy, 40% became seizure-free; 15% discontinued LEV due to adverse events, mostly sedation. This is preliminary evidence that LEV is effective for treating idiopathic generalised epilepsy.
Original language | English (US) |
---|---|
Pages (from-to) | 617-620 |
Number of pages | 4 |
Journal | Seizure |
Volume | 12 |
Issue number | 8 |
DOIs | |
State | Published - Dec 2003 |
Keywords
- Generalised epilepsy
- Levetiracetam
- Seizures
ASJC Scopus subject areas
- Neurology
- Clinical Neurology