Levator Superioris Muscle Function in Involutional Blepharoptosis

Luciano S. Pereira, Thomas N. Hwang, Robert C. Kersten, Kathryn Ray, Timothy J. McCulley

Research output: Contribution to journalArticlepeer-review


Purpose: To assess the role of muscular degeneration, we evaluated the correlation between ptosis severity and levator muscle function. Design: Retrospective cohort study. Methods: The medical records of 136 patients (53 men and 83 women; mean age, 67 years) with acquired blepharoptosis were reviewed for levator function (LF), margin reflex distance (MRD), age, and gender. Multivariate linear regression was performed for statistical analysis. Results: A significant correlation (P < .001) was seen between MRD (mean, 1.0 + 1.0 mm; range, -3.0 to 3.0 mm) and LF (mean, 15.0 + 1.0 mm; range, 11.0 to 20.0 mm). On average, a 0.5-mm reduction in LF was observed for each 1.0-mm decrease in MRD. This was independent to other variables assessed. Conclusions: In patients with involutional blepharoptosis, a directly proportional decrease in levator function and eyelid height was observed. This may implicate an abnormality of the levator muscle itself as a contributing factor in the development of involutional blepharoptosis.

Original languageEnglish (US)
Pages (from-to)1095-1098.e2
JournalAmerican journal of ophthalmology
Issue number6
StatePublished - Jun 2008
Externally publishedYes

ASJC Scopus subject areas

  • Ophthalmology


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