Levation of serum macrophage colony stimulating factor level in patients with Alzheimer's disease

JianMin Zhang, QingLi Kong, ZhenXin Zhang, PingJiang Ge, DeNian Ba, Wei He

Research output: Contribution to journalArticle

Abstract

There was impairment of immune function in patients with Alzheimer's disease (AD), and the perturbation of immune system was involved in the pathogenesis of AD. To investigate the mechanism of the impairment of immune function in AD patients, we analyzed the levels of serum IL-1β, IL-6, TNF-α, and M-CSF in AD patients. The results demonstrated that levels of serum M-CSF were significantly increased in AD patients compared with healthy controls (P

Original languageEnglish (US)
Pages (from-to)61-69
Number of pages9
JournalNeuroscience Research Communications
Volume32
Issue number1
DOIs
StatePublished - Jan 2003
Externally publishedYes

Fingerprint

Macrophage Colony-Stimulating Factor
Alzheimer Disease
Serum
Immune System Diseases
Interleukin-1
Interleukin-6

Keywords

  • Alzheimer's disease
  • Macrophage colony stimulating factor

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Levation of serum macrophage colony stimulating factor level in patients with Alzheimer's disease. / Zhang, JianMin; Kong, QingLi; Zhang, ZhenXin; Ge, PingJiang; Ba, DeNian; He, Wei.

In: Neuroscience Research Communications, Vol. 32, No. 1, 01.2003, p. 61-69.

Research output: Contribution to journalArticle

Zhang, JianMin ; Kong, QingLi ; Zhang, ZhenXin ; Ge, PingJiang ; Ba, DeNian ; He, Wei. / Levation of serum macrophage colony stimulating factor level in patients with Alzheimer's disease. In: Neuroscience Research Communications. 2003 ; Vol. 32, No. 1. pp. 61-69.
@article{4622e692deb24452ad47dd5fcb53ee8c,
title = "Levation of serum macrophage colony stimulating factor level in patients with Alzheimer's disease",
abstract = "There was impairment of immune function in patients with Alzheimer's disease (AD), and the perturbation of immune system was involved in the pathogenesis of AD. To investigate the mechanism of the impairment of immune function in AD patients, we analyzed the levels of serum IL-1β, IL-6, TNF-α, and M-CSF in AD patients. The results demonstrated that levels of serum M-CSF were significantly increased in AD patients compared with healthy controls (P",
keywords = "Alzheimer's disease, Macrophage colony stimulating factor",
author = "JianMin Zhang and QingLi Kong and ZhenXin Zhang and PingJiang Ge and DeNian Ba and Wei He",
year = "2003",
month = "1",
doi = "10.1002/nrc.10059",
language = "English (US)",
volume = "32",
pages = "61--69",
journal = "Neuroscience Research Communications",
issn = "0893-6609",
publisher = "John Wiley and Sons Inc.",
number = "1",

}

TY - JOUR

T1 - Levation of serum macrophage colony stimulating factor level in patients with Alzheimer's disease

AU - Zhang, JianMin

AU - Kong, QingLi

AU - Zhang, ZhenXin

AU - Ge, PingJiang

AU - Ba, DeNian

AU - He, Wei

PY - 2003/1

Y1 - 2003/1

N2 - There was impairment of immune function in patients with Alzheimer's disease (AD), and the perturbation of immune system was involved in the pathogenesis of AD. To investigate the mechanism of the impairment of immune function in AD patients, we analyzed the levels of serum IL-1β, IL-6, TNF-α, and M-CSF in AD patients. The results demonstrated that levels of serum M-CSF were significantly increased in AD patients compared with healthy controls (P

AB - There was impairment of immune function in patients with Alzheimer's disease (AD), and the perturbation of immune system was involved in the pathogenesis of AD. To investigate the mechanism of the impairment of immune function in AD patients, we analyzed the levels of serum IL-1β, IL-6, TNF-α, and M-CSF in AD patients. The results demonstrated that levels of serum M-CSF were significantly increased in AD patients compared with healthy controls (P

KW - Alzheimer's disease

KW - Macrophage colony stimulating factor

UR - http://www.scopus.com/inward/record.url?scp=0037229487&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0037229487&partnerID=8YFLogxK

U2 - 10.1002/nrc.10059

DO - 10.1002/nrc.10059

M3 - Article

AN - SCOPUS:0037229487

VL - 32

SP - 61

EP - 69

JO - Neuroscience Research Communications

JF - Neuroscience Research Communications

SN - 0893-6609

IS - 1

ER -