Abstract
Since the beginning of time, microorganisms have been devising ways to bypass detection and destruction by our immune system. Therefore, it is no surprise that along with the identification of the cellular antiviral protein APOBEC3G (A3G) has come the recognition of the viral solution to this assault. Here, we review the research that led up to the identification of A3G and the mechanism that the human immunodeficiency virus protein Vif developed to evade A3G's antiviral activities.
Original language | English (US) |
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Pages (from-to) | 208-212 |
Number of pages | 5 |
Journal | International journal of hematology |
Volume | 83 |
Issue number | 3 |
DOIs | |
State | Published - Apr 2006 |
Keywords
- APOBEC3
- Cytidine deaminase
- HIV
- Vif
ASJC Scopus subject areas
- Hematology