Learning, memory, and executive control in individuals with obstructive sleep apnea syndrome

Cynthia F Salorio, Desiree A. White, Jay Piccirillo, Stephen P. Duntley, Matthew L. Uhles

Research output: Contribution to journalArticle

Abstract

A range of neuropsychological deficits have been identified in individuals with obstructive sleep apnea syndrome (OSAS) and have been related to disruptions in function of the frontal cortex of the brain. We hypothesized that impairments in the use of strategic, frontally-mediated processes that facilitate learning and memory would be associated with deficits in the long-term episodic memory of verbal material (i.e., word lists). We evaluated 28 adults with OSAS and 24 controls (ranging from 28 to 60 years of age) using the California Verbal Learning Test. General executive abilities were assessed using the Wisconsin Card Sorting Test, Letter fluency, and Category fluency. Individuals with OSAS exhibited poorer recall across learning trials, less efficient use of semantic clustering, and poorer use of semantic cues. Retention of previously encoded information and recognition, however, were intact. With the exception of letter fluency, deficits were not observed in general executive control. Results are discussed within the context of disruptions in the interactions between long-term memory and executive abilities that are subserved by frontal and distal brain regions.

Original languageEnglish (US)
Pages (from-to)93-100
Number of pages8
JournalJournal of Clinical and Experimental Neuropsychology
Volume24
Issue number1
DOIs
StatePublished - 2002
Externally publishedYes

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Executive Function
Obstructive Sleep Apnea
Aptitude
Long-Term Memory
Learning
Semantics
Verbal Learning
Episodic Memory
Brain
Frontal Lobe
Cues
Cluster Analysis

ASJC Scopus subject areas

  • Clinical Neurology
  • Neurology
  • Psychology(all)
  • Clinical Psychology

Cite this

Learning, memory, and executive control in individuals with obstructive sleep apnea syndrome. / Salorio, Cynthia F; White, Desiree A.; Piccirillo, Jay; Duntley, Stephen P.; Uhles, Matthew L.

In: Journal of Clinical and Experimental Neuropsychology, Vol. 24, No. 1, 2002, p. 93-100.

Research output: Contribution to journalArticle

Salorio, Cynthia F ; White, Desiree A. ; Piccirillo, Jay ; Duntley, Stephen P. ; Uhles, Matthew L. / Learning, memory, and executive control in individuals with obstructive sleep apnea syndrome. In: Journal of Clinical and Experimental Neuropsychology. 2002 ; Vol. 24, No. 1. pp. 93-100.
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