TY - JOUR
T1 - Lean mass and fat mass as contributors to physical fitness in an overweight and obese African American population
AU - Yanek, Lisa R.
AU - Vaidya, Dhananjay
AU - Kral, Brian G.
AU - Dobrosielski, Devon A.
AU - Moy, Taryn F.
AU - Stewart, Kerry J.
AU - Becker, Diane M.
N1 - Funding Information:
This study was supported by grant # HL089474-01A1 from the National Institutes of Health/National Heart, Lung, and Blood Institute and grant # UL1 RR 025005 from the National Center for Research Resources and the National Center for Advancing Translational Sciences, National Institutes of Health. The content is solely the responsibility of the authors and does not necessarily represent the official views of the NIH. None of the authors have any financial or personal conflicts of interest to disclose which are relevant to this manuscript.
Publisher Copyright:
© 2016 International Society on Hypertension in Blacks.
PY - 2015/3/1
Y1 - 2015/3/1
N2 - Objective: To determine the association of lean vs fat mass with fitness in healthy, overweight and obese African Americans from families with early-onset coronary disease. Design: Cross-sectional study. Setting: Baltimore, Maryland. Participants: 191 healthy, overweight, sedentary African Americans (69% women; aged 44.8 ± 11 years; body mass index 34 6 5 kg/m2). Main Outcome Measures: Anthropometrics, smoking, blood pressure, lipids, c-reactive protein, and glucose were assessed with standard methods; body composition was determined by dual energy X-ray absorptiometry; cardiorespiratory fitness was expressed as VO2peak attained during a maximal treadmill test. Results: In both men and women, greater lean mass was independently associated with higher VO2peak (P<.05) and explained .21% of the variance in VO2peak, adjusted for body mass index, fat mass, important covariables, and nonindependence of families. Conclusions: In this cross-sectional study, lean mass was the key determinant of cardiorespiratory fitness, independent of sex, age, and magnitude of obesity. These data provide a strong rationale for examining whether interventions that increase lean mass may also improve fitness, even among high-risk overweight and obese African Americans.
AB - Objective: To determine the association of lean vs fat mass with fitness in healthy, overweight and obese African Americans from families with early-onset coronary disease. Design: Cross-sectional study. Setting: Baltimore, Maryland. Participants: 191 healthy, overweight, sedentary African Americans (69% women; aged 44.8 ± 11 years; body mass index 34 6 5 kg/m2). Main Outcome Measures: Anthropometrics, smoking, blood pressure, lipids, c-reactive protein, and glucose were assessed with standard methods; body composition was determined by dual energy X-ray absorptiometry; cardiorespiratory fitness was expressed as VO2peak attained during a maximal treadmill test. Results: In both men and women, greater lean mass was independently associated with higher VO2peak (P<.05) and explained .21% of the variance in VO2peak, adjusted for body mass index, fat mass, important covariables, and nonindependence of families. Conclusions: In this cross-sectional study, lean mass was the key determinant of cardiorespiratory fitness, independent of sex, age, and magnitude of obesity. These data provide a strong rationale for examining whether interventions that increase lean mass may also improve fitness, even among high-risk overweight and obese African Americans.
KW - African Americans
KW - Body composition
KW - Obesity
KW - Physical fitness
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M3 - Article
C2 - 26118151
AN - SCOPUS:84938686822
SN - 1049-510X
VL - 25
SP - 214
EP - 219
JO - Ethnicity and Disease
JF - Ethnicity and Disease
IS - 2
ER -