Lateralization of dementia of depression in stroke patients

K. Bolla-Wilson, R. G. Robinson, S. E. Starkstein, J. Boston, T. R. Price

Research output: Contribution to journalArticlepeer-review

112 Scopus citations


In a group of stroke patients with left-hemisphere lesions, those with major depression performed significantly below nondepressed patients on four of nine cognitive domains examined with a neuropsychological test battery. Among patients with right-hemisphere stroke, those with major depression did not perform below nondepressed patients on any of the nine cognitive domains. The differential effect of depression on cognitive performance between left- and right-hemisphere lesion groups could not be accounted for by demographic variables, neurological symptoms, lesion location, or lesion size. Poststroke major depression appeared to produce a decline in cognitive performance or dementia of depression that depended on the laterality of the lesion.

Original languageEnglish (US)
Pages (from-to)627-634
Number of pages8
JournalAmerican Journal of Psychiatry
Issue number5
StatePublished - 1989

ASJC Scopus subject areas

  • Psychiatry and Mental health


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