Lateral ventricular enlargement associated with persistent unemployment and negative symptoms in both schizophrenia and bipolar disorder

Godfrey D. Pearlson, David J. Garbacz, William R. Breakey, Hyo S. Ahn, J. Raymond DePaulo

Research output: Contribution to journalArticlepeer-review

Abstract

Forty-six patients with schizophrenia or bipolar disorder and 46 individually matched normal volunteers underwent computed tomographic (CT) scans of the head. The ventricular-to-brain ratio was strongly associated with persistent unemployment and negative symptoms in both patient groups. Previous findings of relative lateral ventricular enlargement in a proportion of schizophrenic and bipolar patients were also replicated. Implications of the relationship between CT changes and chronic unemployment among the patients are discussed.

Original languageEnglish (US)
Pages (from-to)1-9
Number of pages9
JournalPsychiatry research
Volume12
Issue number1
DOIs
StatePublished - May 1984

Keywords

  • Computed tomography
  • bipolar illness
  • chronic unemployment
  • negative symptoms
  • schizophrenia
  • ventricular-to-brain ratio

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Biological Psychiatry

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