Latent Mycobacterium tuberculosis - Persistence, patience, and winning by waiting

Research output: Contribution to journalArticle

Abstract

Mycobacterium tuberculosis is a globally successful pathogen due to its ability to persist for long periods of time unrecognized by the human immune system. The panoply of genes that allows the organism to enter latency and then re-emerge later during endogenous reinfection are now being elucidated. Novel antimicrobials and vaccines will need to target these mycobacterial pathogenic mechanisms to suceed against tuberculosis.

Original languageEnglish (US)
Pages (from-to)1327-1329
Number of pages3
JournalNature Medicine
Volume6
Issue number12
DOIs
StatePublished - 2000

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Latent Tuberculosis
Immune system
Pathogens
Mycobacterium tuberculosis
Immune System
Tuberculosis
Vaccines
Genes

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Medicine(all)

Cite this

Latent Mycobacterium tuberculosis - Persistence, patience, and winning by waiting. / Manabe, Yukari C; Bishai, William Ramses.

In: Nature Medicine, Vol. 6, No. 12, 2000, p. 1327-1329.

Research output: Contribution to journalArticle

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