Lasting neuropsychiatric sequelae of ( ± )methylenedioxymethamphetamine (‘ecstasy’) in recreational users

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Abstract

Two persons are described who demonstrated prolonged neuropsychiatric syndromes after the ingestion of large doses of ( ± )-3,4-methylenedioxymeth amphetamine (MDMA), a recreationally used amphetamine analog. These cases suggest that MDMA, known to be neurotoxic to serotonin neurons in several experimental animals, may also produce untoward effects in humans. In addition, they provide evidence that ingestion of large doses of MDMA can produce lasting adverse functional consequences in vulnerable persons.

Original languageEnglish (US)
Pages (from-to)302-305
Number of pages4
JournalJournal of clinical psychopharmacology
Volume11
Issue number5
DOIs
StatePublished - Oct 1991

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Pharmacology (medical)

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