TY - JOUR
T1 - Laser Flare Photometry
T2 - A Useful Tool for Monitoring Patients with Juvenile Idiopathic Arthritis-associated Uveitis
AU - Orès, Raphaëlle
AU - Terrada, Céline
AU - Errera, Marie Hélène
AU - Thorne, Jennifer E.
AU - Doukhan, Raphaël
AU - Cassoux, Nathalie
AU - Penaud, Benjamin
AU - LeHoang, Phuc
AU - Quartier, Pierre Marie
AU - Bodaghi, Bahram
N1 - Publisher Copyright:
© 2020 Taylor & Francis Group, LLC.
Copyright:
Copyright 2020 Elsevier B.V., All rights reserved.
PY - 2020
Y1 - 2020
N2 - Purpose: We evaluated laser flare photometry (LFP) values in patients with juvenile idiopathic arthritis (JIA)-associated uveitis. Methods: Retrospective study. A decrease of the LFP value between baseline visit and 1 month after anti-inflammatory treatment intensification allowed us to define two groups of patients: group 1 (decreased LFP value ≥50%) and group 2 (<50%). We evaluated the prevalence of vision-threatening complications in both groups. Results: Fifty-four patients (87 eyes) were followed for 9.9 ± 5 years. Group 1 eyes (n = 54) had significantly fewer ocular complications than group 2 eyes (n = 33) at both 5 years visit (p = .03) and final visit (p = .047). At the final visit, group 2 eyes had significantly more band keratopathy, trabeculectomy, cataract surgery, glaucoma and papille edema. Group 1 eyes kept a better visual acuity (p < .0001). Conclusion: The decrease of LFP values ≥50% of the initial value 1 month after treatment intensification is a good early prognostic factor.
AB - Purpose: We evaluated laser flare photometry (LFP) values in patients with juvenile idiopathic arthritis (JIA)-associated uveitis. Methods: Retrospective study. A decrease of the LFP value between baseline visit and 1 month after anti-inflammatory treatment intensification allowed us to define two groups of patients: group 1 (decreased LFP value ≥50%) and group 2 (<50%). We evaluated the prevalence of vision-threatening complications in both groups. Results: Fifty-four patients (87 eyes) were followed for 9.9 ± 5 years. Group 1 eyes (n = 54) had significantly fewer ocular complications than group 2 eyes (n = 33) at both 5 years visit (p = .03) and final visit (p = .047). At the final visit, group 2 eyes had significantly more band keratopathy, trabeculectomy, cataract surgery, glaucoma and papille edema. Group 1 eyes kept a better visual acuity (p < .0001). Conclusion: The decrease of LFP values ≥50% of the initial value 1 month after treatment intensification is a good early prognostic factor.
KW - Uveitis
KW - juvenile idiopathic arthritis
KW - laser flare photometry
UR - http://www.scopus.com/inward/record.url?scp=85089780711&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85089780711&partnerID=8YFLogxK
U2 - 10.1080/09273948.2020.1792511
DO - 10.1080/09273948.2020.1792511
M3 - Article
C2 - 32835572
AN - SCOPUS:85089780711
JO - Ocular Immunology and Inflammation
JF - Ocular Immunology and Inflammation
SN - 0927-3948
ER -