Larger Optic Nerve Heads Have More Nerve Fibers in Normal Monkey Eyes

Harry A. Quigley; Anne L. Coleman; Mary Ellen Dorman Pease

doi:10.1001/archopht.1991.01080100121056

Larger Optic Nerve Heads Have More Nerve Fibers in Normal Monkey Eyes

Harry A. Quigley, Anne L. Coleman, Mary Ellen Dorman Pease

School of Medicine

Research output: Contribution to journal › Article › peer-review

104 Scopus citations

Abstract

The cup-to-disc ratio and the neural rim area are used to detect glaucoma damage to the optic nerve. Both parameters are dependent on the size of the optic disc and on the number of optic nerve fibers. We compared the size of the disc in fundus photographs with the number of nerve fibers in 25 normal monkey eyes. The number of fibers increased linearly with an increasing disc area. One must know the size of the optic disc to evaluate properly the cup-to-disc ratio or neural rim area.

Original language	English (US)
Pages (from-to)	1441-1443
Number of pages	3
Journal	Archives of ophthalmology
Volume	109
Issue number	10
DOIs	https://doi.org/10.1001/archopht.1991.01080100121056
State	Published - Oct 1991

ASJC Scopus subject areas

Ophthalmology

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10.1001/archopht.1991.01080100121056

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abstract = "The cup-to-disc ratio and the neural rim area are used to detect glaucoma damage to the optic nerve. Both parameters are dependent on the size of the optic disc and on the number of optic nerve fibers. We compared the size of the disc in fundus photographs with the number of nerve fibers in 25 normal monkey eyes. The number of fibers increased linearly with an increasing disc area. One must know the size of the optic disc to evaluate properly the cup-to-disc ratio or neural rim area.",

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AB - The cup-to-disc ratio and the neural rim area are used to detect glaucoma damage to the optic nerve. Both parameters are dependent on the size of the optic disc and on the number of optic nerve fibers. We compared the size of the disc in fundus photographs with the number of nerve fibers in 25 normal monkey eyes. The number of fibers increased linearly with an increasing disc area. One must know the size of the optic disc to evaluate properly the cup-to-disc ratio or neural rim area.

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Larger Optic Nerve Heads Have More Nerve Fibers in Normal Monkey Eyes

Abstract

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