Large-scale quarantine following biological terrorism in the United States: Scientific examination, logistic and legal limits, and possible consequences

Joseph Barbera, Anthony Macintyre, Craig DeAtley, Larry Gostin, Tom Inglesby, Tara O'Toole, Kevin Tonat, Marci Layton

Research output: Contribution to journalArticlepeer-review

Abstract

Concern for potential bioterrorist attacks causing mass casualties has increased recently. Particular attention has been paid to scenarios in which a biological agent capable of person-to-person transmission, such as small-pox, is intentionally released among civilians. Multiple public health interventions are possible to effect disease containment in this context. One disease control measure that has been regularly proposed in various settings is the imposition of large-scale or geographic quarantine on the potentially exposed population. Although large-scale quarantine has not been implemented in recent US history, it has been used on a small scale in biological hoaxes, and it has been invoked in federally sponsored bioterrorism exercises. This article reviews the scientific principles that are relevant to the likely effectiveness of quarantine, the logistic barriers to its implementation, legal issues that a large-scale quarantine raises, and possible adverse consequences that might result from quarantine action. Imposition of large-scale quarantin - compulsory sequestration of groups of possibly exposed persons or human confinement within certain geographic areas to prevent spread of contagious disease - should not be considered a primary public health strategy in most imaginable circumstances. In the majority of contexts, other less extreme public health actions are likely to be more effective and create fewer unintended adverse consequences than quarantine. Actions and areas for future research, policy development, and response planning efforts are provided.

Original languageEnglish (US)
Pages (from-to)2711-2717
Number of pages7
JournalJournal of the American Medical Association
Volume286
Issue number21
DOIs
StatePublished - Dec 5 2001

ASJC Scopus subject areas

  • Medicine(all)

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