Large nested variant of urothelial carcinoma

23 cases mimicking von brunn nests and inverted growth pattern of noninvasive papillary urothelial carcinoma

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Abstract

We describe a rare pattern of urothelial carcinoma (UC) invasion consisting of large, irregular to regular nests, with bland cytology. We prospectively retrieved 23 cases of large nested UC from one of the author's consult files (2001 to 2010). The mean patient age was 63.7 years (39 to 89 y), and 86% were men. There were 18 cases with transurethral resection of the bladder, 2 nephroureterectomy specimens, and 3 radical cystectomy (RCs) specimens. A surface component was present in 19 of 23 cases, with 16 low-grade papillary UCs, 2 low-grade papillary UCs with

Original languageEnglish (US)
Pages (from-to)1337-1342
Number of pages6
JournalAmerican Journal of Surgical Pathology
Volume35
Issue number9
DOIs
StatePublished - Sep 2011

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Papillary Carcinoma
Carcinoma
Cystectomy
Growth
Cell Biology
Urinary Bladder

Keywords

  • bladder neoplasm
  • nested variant
  • urothelial carcinoma

ASJC Scopus subject areas

  • Anatomy
  • Pathology and Forensic Medicine
  • Surgery

Cite this

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abstract = "We describe a rare pattern of urothelial carcinoma (UC) invasion consisting of large, irregular to regular nests, with bland cytology. We prospectively retrieved 23 cases of large nested UC from one of the author's consult files (2001 to 2010). The mean patient age was 63.7 years (39 to 89 y), and 86{\%} were men. There were 18 cases with transurethral resection of the bladder, 2 nephroureterectomy specimens, and 3 radical cystectomy (RCs) specimens. A surface component was present in 19 of 23 cases, with 16 low-grade papillary UCs, 2 low-grade papillary UCs with",
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