Large-Cell Neuroendocrine Carcinoma of the Lung: An Aggressive Neuroendocrine Lung Cancer

Felix G. Fernandez, Richard J Battafarano

Research output: Contribution to journalArticle

Abstract

Large cell neuroendocrine carcinoma (LCNEC) is part of the neuroendocrine spectrum of pulmonary tumors. This increasingly recognized tumor has been reported to have 5-year actuarial survival rates following resection that are worse than those described for other variants of non-small cell lung cancer (NSCLC). Therefore, debate has emerged regarding whether the tumors should be classified and treated as NSCLC or small-cell lung cancer. This article reviews the tumor characterization, biology, presentation and diagnosis, surgical therapy, results of therapy, and long term prognosis of patients with LCNEC.

Original languageEnglish (US)
Pages (from-to)206-210
Number of pages5
JournalSeminars in Thoracic and Cardiovascular Surgery
Volume18
Issue number3
DOIs
StatePublished - 2006
Externally publishedYes

Fingerprint

Neuroendocrine Carcinoma
Large Cell Carcinoma
Lung Neoplasms
Lung
Non-Small Cell Lung Carcinoma
Neoplasms
Small Cell Lung Carcinoma
Survival Rate
Therapeutics

Keywords

  • large cell neuroendocrine carcinoma
  • neuroendocrine spectrum
  • non-small cell lung cancer
  • pulmonary tumors

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Large-Cell Neuroendocrine Carcinoma of the Lung : An Aggressive Neuroendocrine Lung Cancer. / Fernandez, Felix G.; Battafarano, Richard J.

In: Seminars in Thoracic and Cardiovascular Surgery, Vol. 18, No. 3, 2006, p. 206-210.

Research output: Contribution to journalArticle

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