Laparoscopic splenectomy for secondary cytoreduction of ovarian cancer in a woman with localized splenic recurrence

Stefany Acosta-Torres, Amanda N. Fader

Research output: Contribution to journalArticle

Abstract

Objective/background: Laparoscopic splenectomy is a potential surgical option for the treatment of isolated gynecologic cancer recurrence to the spleen [1–7]. The purpose of this video is to demonstrate a step-by-step approach for laparoscopic splenectomy in the setting of recurrent, oligometastatic ovarian cancer. Methods: We present the case of a 47-year-old female with recurrent, platinum-sensitive high-grade serous ovarian cancer. A computer tomographic scan demonstrated an isolated 1.5 × 1.0 cm recurrence in the splenic hilum. A laparoscopic secondary cytoreduction with splenectomy was planned. The surgical procedure was recorded via the video camera tower, and the key steps for a laparoscopic splenectomy were identified and highlighted. Results: The indications for secondary cytoreductive surgery, the appropriate candidates for minimally invasive surgery, patient positioning principles to set the surgeon up for success, and left upper quadrant anatomy are reviewed. In the surgical case and in the setting of hilar disease, the technique and rationale for ligating the major splenic ligaments in a particular order are reviewed. The procedure for isolating and ligating the dominant vascular structures – the splenic artery and vein – are reviewed. Finally, perioperative and oncologic outcomes, including an estimated blood loss of 100 cc, operative time of 3 h, a disease-free interval and “no evidence of disease” status after chemotherapy at 14 months, are emphasized. Conclusions: In this video, both anatomical references and the surgical technique for a laparoscopic splenectomy in the setting of recurrent ovarian cancer are illustrated. We demonstrate that laparoscopic splenectomy is feasible and safe with proper patient selection and positioning as well as meticulous surgical technique.

Original languageEnglish (US)
JournalGynecologic oncology
DOIs
StateAccepted/In press - Jan 1 2020

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Splenectomy
Ovarian Neoplasms
Recurrence
Patient Positioning
Splenic Vein
Splenic Artery
Minimally Invasive Surgical Procedures
Operative Time
Platinum
Ligaments
Patient Selection
Blood Vessels
Anatomy
Spleen
Drug Therapy
Neoplasms

ASJC Scopus subject areas

  • Oncology
  • Obstetrics and Gynecology

Cite this

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title = "Laparoscopic splenectomy for secondary cytoreduction of ovarian cancer in a woman with localized splenic recurrence",
abstract = "Objective/background: Laparoscopic splenectomy is a potential surgical option for the treatment of isolated gynecologic cancer recurrence to the spleen [1–7]. The purpose of this video is to demonstrate a step-by-step approach for laparoscopic splenectomy in the setting of recurrent, oligometastatic ovarian cancer. Methods: We present the case of a 47-year-old female with recurrent, platinum-sensitive high-grade serous ovarian cancer. A computer tomographic scan demonstrated an isolated 1.5 × 1.0 cm recurrence in the splenic hilum. A laparoscopic secondary cytoreduction with splenectomy was planned. The surgical procedure was recorded via the video camera tower, and the key steps for a laparoscopic splenectomy were identified and highlighted. Results: The indications for secondary cytoreductive surgery, the appropriate candidates for minimally invasive surgery, patient positioning principles to set the surgeon up for success, and left upper quadrant anatomy are reviewed. In the surgical case and in the setting of hilar disease, the technique and rationale for ligating the major splenic ligaments in a particular order are reviewed. The procedure for isolating and ligating the dominant vascular structures – the splenic artery and vein – are reviewed. Finally, perioperative and oncologic outcomes, including an estimated blood loss of 100 cc, operative time of 3 h, a disease-free interval and “no evidence of disease” status after chemotherapy at 14 months, are emphasized. Conclusions: In this video, both anatomical references and the surgical technique for a laparoscopic splenectomy in the setting of recurrent ovarian cancer are illustrated. We demonstrate that laparoscopic splenectomy is feasible and safe with proper patient selection and positioning as well as meticulous surgical technique.",
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AB - Objective/background: Laparoscopic splenectomy is a potential surgical option for the treatment of isolated gynecologic cancer recurrence to the spleen [1–7]. The purpose of this video is to demonstrate a step-by-step approach for laparoscopic splenectomy in the setting of recurrent, oligometastatic ovarian cancer. Methods: We present the case of a 47-year-old female with recurrent, platinum-sensitive high-grade serous ovarian cancer. A computer tomographic scan demonstrated an isolated 1.5 × 1.0 cm recurrence in the splenic hilum. A laparoscopic secondary cytoreduction with splenectomy was planned. The surgical procedure was recorded via the video camera tower, and the key steps for a laparoscopic splenectomy were identified and highlighted. Results: The indications for secondary cytoreductive surgery, the appropriate candidates for minimally invasive surgery, patient positioning principles to set the surgeon up for success, and left upper quadrant anatomy are reviewed. In the surgical case and in the setting of hilar disease, the technique and rationale for ligating the major splenic ligaments in a particular order are reviewed. The procedure for isolating and ligating the dominant vascular structures – the splenic artery and vein – are reviewed. Finally, perioperative and oncologic outcomes, including an estimated blood loss of 100 cc, operative time of 3 h, a disease-free interval and “no evidence of disease” status after chemotherapy at 14 months, are emphasized. Conclusions: In this video, both anatomical references and the surgical technique for a laparoscopic splenectomy in the setting of recurrent ovarian cancer are illustrated. We demonstrate that laparoscopic splenectomy is feasible and safe with proper patient selection and positioning as well as meticulous surgical technique.

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