Laparoscopic retroperitoneal lymph node dissection for stage I and II nonseminomatous germ-cell tumors

Thomas J. Guzzo, Mohamad E Allaf

Research output: Contribution to journalReview article

Abstract

Objectives: Open retroperitoneal lymph node dissection has been traditionally used for the management of patients with nonseminomatous germ-cell tumors (NSGCTs). Over the last decade, laparoscopic retroperitoneal lymph node dissection (LRPLND) has gained popularity in several highly specialized centers. Methods: We retrospectively reviewed the English-language literature with regard to LRPLND. The perioperative and oncologic outcomes for patients with low stage NSGCTs who underwent LRPLND are summarized in this review with particular emphasis on contemporary studies. Results: Initially only used for staging, LRPLND has evolved to a therapeutic procedure capable of replicating the templates used for open RPLND. Perioperative outcomes including operative time, conversion rates and complications improve with surgeon experience and are acceptable at high volume centers. Oncologic outcomes are promising, but require longer term follow-up and the administration of adjuvant chemotherapy in many studies limits comparison to that of the open technique. Conclusion: LRPLND has been demonstrated to be feasible and safe at large volume institutions with experienced laparoscopic surgeons. LRPLND was originally performed as a staging procedure in patients with NSGCTs but has evolved into a therapeutic operation with early reports demonstrating short hospital stays and minimal morbidity. Further studies in larger cohorts of patients with longer term follow up are required to define the exact role of LRPLND.

Original languageEnglish (US)
Pages (from-to)107-114
Number of pages8
JournalTherapeutic Advances in Urology
Volume1
Issue number2
DOIs
StatePublished - 2009

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Keywords

  • laparoscopic retroperitoneal lymph node dissection
  • testicular cancer

ASJC Scopus subject areas

  • Urology

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