Laparo-endoscopic transgastric resection of gastric submucosal tumors

Juan S. Barajas-Gamboa, Geylor Acosta, Thomas J. Savides, Jason K. Sicklick, Syed M.Abbas Fehmi, Alisa M. Coker, Shannon Green, Ryan Broderick, Diego F. Nino, Cristina R. Harnsberger, Martin A. Berducci, Bryan J. Sandler, Mark A. Talamini, Garth R. Jacobsen, Santiago Horgan

Research output: Contribution to journalArticlepeer-review

Abstract

Background: Laparoscopic and endoluminal surgical techniques have evolved and allowed improvements in the methods for treating benign and malignant gastrointestinal diseases. To date, only case reports have been reported on the application of a laparo-endoscopic approach for resecting gastric submucosal tumors (SMT). In this study, we aimed to evaluate the efficacy, safety, and oncologic outcomes of a laparo-endoscopic transgastric approach to resect tumors that would traditionally require either a laparoscopic or open surgical approach. Herein, we present the largest single institution series utilizing this technique for the resection of gastric SMT in North America. Methods: We performed a retrospective review of a prospectively collected patient database. Patients who presented for evaluation of gastric SMT were offered this surgical procedure and informed consents were obtained for participation in the study. Results: Fourteen patients were included in this study between August/2010 and January/2013. Eight (8) patients (57.1 %) were female and the median age was 56 years (range 29–78). Of the 14 cases, 8 patients (57.1 %) underwent laparo-endoscopic resection of SMTs with transgastric extraction, 5 patients (35.7 %) had conversions to traditional laparoscopic surgery, and 1 patient (7.2 %) was abandoned intraoperatively. The median operative time for this cohort was 80 min (range 35–167). Ten patients (71.4 %) had GISTs, 3 (21.4 %) had leiomyomas, and 1 (7.1 %) had schwannoma. There were no intraoperative complications. Two patients had postoperative staple line bleeding that required repeat endoscopy. The median hospital stay was 1 day (range 1–6) and there were no postoperative mortalities. At 12-month follow-up visit, only one GIST patient (10 %) had tumor recurrence. Conclusion: Our experience suggests that this surgical approach is safe and efficient in the resection of gastric SMT with transgastric extraction. This study found no intraoperative complications and optimal oncologic outcomes during the follow-up period. Minimally invasive surgical approaches are emerging as a valid and potentially better approach for resecting malignancies; however, continued investigation is underway to further validate this data.

Original languageEnglish (US)
Pages (from-to)2149-2157
Number of pages9
JournalSurgical endoscopy
Volume29
Issue number8
DOIs
StatePublished - Aug 25 2015

Keywords

  • GIST
  • Laparo-endoscopic surgery
  • Leiomyoma
  • Minimally invasive surgery
  • NOTES
  • Tumor resection

ASJC Scopus subject areas

  • Surgery

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