Langerhans cell histiocytosis of the thyroid: A report of two cases and review of the literature

Robert J. Behrens, Angelique W. Levi, William H. Westra, Deepa Dutta, David S. Cooper

Research output: Contribution to journalArticle

Abstract

Langerhans cell histiocytosis (LCH) is a monoclonal disease of histiocytes that can involve many or very few organ systems. It is a relatively benign disorder with a 3% mortality in adults. LCH rarely involves the thyroid gland. We report two cases, both presenting in males with a goiter. Both patients were treated with subtotal thyroidectomy. The first patient also received radiotherapy to his thyroid bed and scalp. We summarize the prior reported cases of LCH involving the thyroid and review the current treatment modalities used for LCH.

Original languageEnglish (US)
Pages (from-to)697-705
Number of pages9
JournalThyroid
Volume11
Issue number7
DOIs
StatePublished - 2001

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Endocrinology

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