Lack of mutagenicity of vinyl chloride in two strains of neurospora crassa

B. Z. Drozdowicz, P. C. Huang

Research output: Contribution to journalArticlepeer-review

Abstract

No detectable induction of mutations could be found in two strains of Neurospora crassa after their conidia were treated with vinyl chloride, in ethanol solution and in its gaseous form. The results suggest that although N. crassa seems to lack a detectable level of typical microsomal activating system, the addition of exogenous activating systems does not increase mutagenic activity of vinyl chloride in the two strains tested. At the same time these strains were mutated easily by UV and methyl methanesulfonate.

Original languageEnglish (US)
Pages (from-to)43-50
Number of pages8
JournalMutation Research - Fundamental and Molecular Mechanisms of Mutagenesis
Volume48
Issue number1
DOIs
StatePublished - Jan 1977

ASJC Scopus subject areas

  • Molecular Biology
  • Genetics
  • Health, Toxicology and Mutagenesis

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