Lack of induced increase in sister chromatid exchanges in human lymphocytes exposed to in vivo therapeutic ultrasound

Morton W. Miller, Mitra Azadniv, C. Coxt, W. Marcus Miller

Research output: Contribution to journalArticle

Abstract

In 1984 Stella et al. reported that each of 10 patients exposed to therapeutic ultrasound had a statistically significant increase in sister chromatid exchanges (SCEs) at mid- and end of therapy; there was a wide range of clinical symptoms (e.g., elbow epicondylitis to knee arthrosis) in this set of patients. In the present study, a set of 4 patients each with some diagnosis recommending therapeutic ultrasound was similarly tested for SCE induction; an additional set of 4 healthy persons underwent sham-therapeutic ultrasound exposures. For both sets of subjects (patients, nonpatients) there was no increase in the frequency of SCEs.

Original languageEnglish (US)
Pages (from-to)81-83
Number of pages3
JournalUltrasound in Medicine and Biology
Volume17
Issue number1
DOIs
StatePublished - 1991
Externally publishedYes

Keywords

  • Human lymphocytes
  • In vivo therapeutic ultrasound
  • Sister chromatid exchanges

ASJC Scopus subject areas

  • Biophysics
  • Radiological and Ultrasound Technology
  • Acoustics and Ultrasonics

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