Lack of increase in cell transformation frequency of C3H cells after exposure to pulsed ultrasound

W. H. Zhu, M. W. Miller, Christopher Cox

Research output: Contribution to journalArticle

Abstract

Libeskind et al.1 1 Liebeskind, D., Bases, R., Elequin, F., Neubort, S., Leifer, R., Goldberg, R. and Koenigsberg, M. Diagnostic ultrasound: effects on the DNA and growth patterns of animal cells Radiology (1979) 131 177-184 reported that ultrasound from a diagnostic ultrasound unit caused an increase in cell transformation of in vitro C3H cells. The objective of this study was to attempt verification of this result, using the same cell line and a similar ultrasound exposure regimen. Four experiments were undertaken, each involving an ultrasound, X-ray (positive control) and sham exposure regimen. There was no increase in cell transformation frequency with the ultrasound exposure, but a small and statistically significant increase with the X-ray regimen.

Original languageEnglish (US)
Pages (from-to)81-84
Number of pages4
JournalUltrasonics
Volume29
Issue number1
DOIs
StatePublished - 1991
Externally publishedYes

Fingerprint

Ultrasonics
cells
radiology
Cells
cultured cells
animals
X rays
Radiology
x rays
deoxyribonucleic acid
Animals
DNA
Experiments

Keywords

  • cell transformation
  • in vitro ultrasound
  • plating efficiency

ASJC Scopus subject areas

  • Safety, Risk, Reliability and Quality
  • Acoustics and Ultrasonics

Cite this

Lack of increase in cell transformation frequency of C3H cells after exposure to pulsed ultrasound. / Zhu, W. H.; Miller, M. W.; Cox, Christopher.

In: Ultrasonics, Vol. 29, No. 1, 1991, p. 81-84.

Research output: Contribution to journalArticle

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