Lack of effect of simultaneous growth hormone-releasing hormone and naloxone infusions on growth hormone (GH) secretion in normal men

F. Barbetti; M. Cappa; P. Del Balzo; A. Grossi; R. Salvatori; G. Tamburrano

Lack of effect of simultaneous growth hormone-releasing hormone and naloxone infusions on growth hormone (GH) secretion in normal men

F. Barbetti, M. Cappa, P. Del Balzo, A. Grossi, R. Salvatori, G. Tamburrano

Research output: Contribution to journal › Article › peer-review

Abstract

Recent studies (in vitro) have demonstrated that stimulatory effect of GH-RH on somatostatin release from hypothalamic cells in culture is probably mediated by beta-endorphin. Conflicting results are reported on the influence of Naloxone on GH secretion in humans. Our data seems to support the view that opioid receptor blockade is not able to modify GH secretion during GH-RH infusion in normal males.

Original language	English (US)
Pages (from-to)	97-100
Number of pages	4
Journal	Neuroendocrinology Letters
Volume	10
Issue number	2
State	Published - Jan 1 1988
Externally published	Yes

ASJC Scopus subject areas

Endocrinology, Diabetes and Metabolism
Endocrinology
Neurology
Endocrine and Autonomic Systems
Clinical Neurology
Psychiatry and Mental health

Cite this

@article{c0e12dde27574d3e81a79678d991acda,

title = "Lack of effect of simultaneous growth hormone-releasing hormone and naloxone infusions on growth hormone (GH) secretion in normal men",

abstract = "Recent studies (in vitro) have demonstrated that stimulatory effect of GH-RH on somatostatin release from hypothalamic cells in culture is probably mediated by beta-endorphin. Conflicting results are reported on the influence of Naloxone on GH secretion in humans. Our data seems to support the view that opioid receptor blockade is not able to modify GH secretion during GH-RH infusion in normal males.",

author = "F. Barbetti and M. Cappa and {Del Balzo}, P. and A. Grossi and R. Salvatori and G. Tamburrano",

year = "1988",

month = jan,

day = "1",

language = "English (US)",

volume = "10",

pages = "97--100",

journal = "Neuroendocrinology Letters",

issn = "0172-780X",

publisher = "Maghira and Maas Publications",

number = "2",

}

TY - JOUR

T1 - Lack of effect of simultaneous growth hormone-releasing hormone and naloxone infusions on growth hormone (GH) secretion in normal men

AU - Barbetti, F.

AU - Cappa, M.

AU - Del Balzo, P.

AU - Grossi, A.

AU - Salvatori, R.

AU - Tamburrano, G.

PY - 1988/1/1

Y1 - 1988/1/1

N2 - Recent studies (in vitro) have demonstrated that stimulatory effect of GH-RH on somatostatin release from hypothalamic cells in culture is probably mediated by beta-endorphin. Conflicting results are reported on the influence of Naloxone on GH secretion in humans. Our data seems to support the view that opioid receptor blockade is not able to modify GH secretion during GH-RH infusion in normal males.

AB - Recent studies (in vitro) have demonstrated that stimulatory effect of GH-RH on somatostatin release from hypothalamic cells in culture is probably mediated by beta-endorphin. Conflicting results are reported on the influence of Naloxone on GH secretion in humans. Our data seems to support the view that opioid receptor blockade is not able to modify GH secretion during GH-RH infusion in normal males.

UR - http://www.scopus.com/inward/record.url?scp=0023917833&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0023917833&partnerID=8YFLogxK

M3 - Article

AN - SCOPUS:0023917833

SN - 0172-780X

VL - 10

SP - 97

EP - 100

JO - Neuroendocrinology Letters

JF - Neuroendocrinology Letters

IS - 2

ER -

Lack of effect of simultaneous growth hormone-releasing hormone and naloxone infusions on growth hormone (GH) secretion in normal men

Abstract

ASJC Scopus subject areas

Other files and links

Fingerprint

Cite this