Lack of effect of ovarian denervation on ovulation and pregnancy in the rabbit

S. Weiner, K. H. Wright, E. E. Wallach

Research output: Contribution to journalArticlepeer-review

Abstract

Following unilateral ovarian denervation by ovarian artery stripping in female rabbits, ovulation and pregnancy were achieved within 3 days of denervation. Three weeks later, at repeat laparotomy, ovarian dimensions and the numbers of corpora lutea and pregnancies were noted. Fluorescent histochemical studies confirmed complete adrenergic denervation in five of the rabbits' ovaries. There was no significant difference in ovarian dimensions, numbers of corpora lutea and pregnancies, or the excess of corpora lutea over implantations when the intact control side was compared with the denervated side. The control ovaries demonstrated an average of 5 corpora lutea/ovary and an average of 3.4 conceptuses in the adjacent uterine horn, while the numbers on the denervated side were 5 and 3.2, respectively. Although these findings demonstrate that central neural efferent control is not essential for the occurrence of pregnancy after mating in the rabbit, the potential significance of ovarian neuromuscular mechanisms in these functions is discussed, and future studies are suggested.

Original languageEnglish (US)
Pages (from-to)1083-1087
Number of pages5
JournalFertility and sterility
Volume26
Issue number11
DOIs
StatePublished - 1975
Externally publishedYes

ASJC Scopus subject areas

  • Reproductive Medicine
  • Obstetrics and Gynecology

Fingerprint

Dive into the research topics of 'Lack of effect of ovarian denervation on ovulation and pregnancy in the rabbit'. Together they form a unique fingerprint.

Cite this