Lack of effect of hypercapnic acidosis on elasticity of cat papillary muscles

Alicia R. Mattiazzi, Horacio E. Cingolani, Thomas P. Graham

Research output: Contribution to journalArticlepeer-review

Abstract

Summary: Changes in external pH from 7.40 to 6.95 obtained by changing the pCO2 of the medium at constant bicarbonate concentration produced in cat papillary muscles a significant decrease in isometric tension with no changes in time to peak tension. Active and resting stiffness, as determined by two different methods, did not change under conditions of hypercapnic acidosis.

Original languageEnglish (US)
Pages (from-to)559-567
Number of pages9
JournalCardiovascular Research
Volume11
Issue number6
DOIs
StatePublished - Nov 1977
Externally publishedYes

ASJC Scopus subject areas

  • Statistics, Probability and Uncertainty
  • Applied Mathematics
  • Physiology (medical)
  • Physiology
  • Cardiology and Cardiovascular Medicine

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