Labon-gur (common salt and brown sugar) oral rehydration solution in the treatment of diarrhoea in adults

M. R. Islam, William Greenough, M. Mujibur Rahaman, A. K. Choudhury, David Allen Sack

Research output: Contribution to journalArticle

Abstract

A clinical trial was carried out on 50 adult patients in Dacca, Bangladesh; with moderate dehydration due to diarrhoea of varying oetiology to observe the efficacy of an oral solution containing only common salt (labon) and unrefined sugar (gur). Failure was defined as not correcting initial dehydration, not maintaining hydration or developing an electrolyte imbalance at any time during the study period. Volume loss was corrected in less than 8 hours by drinking the labon-gur solution. Acidosis (CO2 less than 20 mEq/l) was not corrected in 20% of patients even after 48 hours of therapy. The severity and persistence of acidosis was significantly correlated with the stool volume. Our findings indicate that adult patients, with diarrhoea and dehydration are readily rehydrated, if they drink a simple salt-sugar solution. When fluid losses exceed 50 ml/kg/24 hours acidosis will not be corrected for several days. The failure to correct acidosis promptly may not be of great clinical importance in adults with mild diarrhoea, and in such cases sodium bicarbonate may not be needed. More serious consequences of sustained acidosis may result in children and severely affected adults. This requires further evaluation.

Original languageEnglish (US)
Pages (from-to)41-45
Number of pages5
JournalJournal of Tropical Medicine and Hygiene
Volume83
Issue number1
StatePublished - 1980
Externally publishedYes

Fingerprint

Rehydration Solutions
rehydration
Fluid Therapy
Acidosis
Dehydration
Sugars
Diarrhea
sugar
Salts
dehydration
salt
Sodium bicarbonate
Hydration
Therapeutics
drinking
Electrolytes
hydration
bicarbonate
Sodium Bicarbonate
Bangladesh

ASJC Scopus subject areas

  • Parasitology
  • Infectious Diseases

Cite this

Labon-gur (common salt and brown sugar) oral rehydration solution in the treatment of diarrhoea in adults. / Islam, M. R.; Greenough, William; Mujibur Rahaman, M.; Choudhury, A. K.; Sack, David Allen.

In: Journal of Tropical Medicine and Hygiene, Vol. 83, No. 1, 1980, p. 41-45.

Research output: Contribution to journalArticle

@article{e08b783046aa4220a16f63c0192780a6,
title = "Labon-gur (common salt and brown sugar) oral rehydration solution in the treatment of diarrhoea in adults",
abstract = "A clinical trial was carried out on 50 adult patients in Dacca, Bangladesh; with moderate dehydration due to diarrhoea of varying oetiology to observe the efficacy of an oral solution containing only common salt (labon) and unrefined sugar (gur). Failure was defined as not correcting initial dehydration, not maintaining hydration or developing an electrolyte imbalance at any time during the study period. Volume loss was corrected in less than 8 hours by drinking the labon-gur solution. Acidosis (CO2 less than 20 mEq/l) was not corrected in 20{\%} of patients even after 48 hours of therapy. The severity and persistence of acidosis was significantly correlated with the stool volume. Our findings indicate that adult patients, with diarrhoea and dehydration are readily rehydrated, if they drink a simple salt-sugar solution. When fluid losses exceed 50 ml/kg/24 hours acidosis will not be corrected for several days. The failure to correct acidosis promptly may not be of great clinical importance in adults with mild diarrhoea, and in such cases sodium bicarbonate may not be needed. More serious consequences of sustained acidosis may result in children and severely affected adults. This requires further evaluation.",
author = "Islam, {M. R.} and William Greenough and {Mujibur Rahaman}, M. and Choudhury, {A. K.} and Sack, {David Allen}",
year = "1980",
language = "English (US)",
volume = "83",
pages = "41--45",
journal = "Journal of Tropical Medicine and Hygiene",
issn = "0022-5304",
publisher = "Wiley-Blackwell",
number = "1",

}

TY - JOUR

T1 - Labon-gur (common salt and brown sugar) oral rehydration solution in the treatment of diarrhoea in adults

AU - Islam, M. R.

AU - Greenough, William

AU - Mujibur Rahaman, M.

AU - Choudhury, A. K.

AU - Sack, David Allen

PY - 1980

Y1 - 1980

N2 - A clinical trial was carried out on 50 adult patients in Dacca, Bangladesh; with moderate dehydration due to diarrhoea of varying oetiology to observe the efficacy of an oral solution containing only common salt (labon) and unrefined sugar (gur). Failure was defined as not correcting initial dehydration, not maintaining hydration or developing an electrolyte imbalance at any time during the study period. Volume loss was corrected in less than 8 hours by drinking the labon-gur solution. Acidosis (CO2 less than 20 mEq/l) was not corrected in 20% of patients even after 48 hours of therapy. The severity and persistence of acidosis was significantly correlated with the stool volume. Our findings indicate that adult patients, with diarrhoea and dehydration are readily rehydrated, if they drink a simple salt-sugar solution. When fluid losses exceed 50 ml/kg/24 hours acidosis will not be corrected for several days. The failure to correct acidosis promptly may not be of great clinical importance in adults with mild diarrhoea, and in such cases sodium bicarbonate may not be needed. More serious consequences of sustained acidosis may result in children and severely affected adults. This requires further evaluation.

AB - A clinical trial was carried out on 50 adult patients in Dacca, Bangladesh; with moderate dehydration due to diarrhoea of varying oetiology to observe the efficacy of an oral solution containing only common salt (labon) and unrefined sugar (gur). Failure was defined as not correcting initial dehydration, not maintaining hydration or developing an electrolyte imbalance at any time during the study period. Volume loss was corrected in less than 8 hours by drinking the labon-gur solution. Acidosis (CO2 less than 20 mEq/l) was not corrected in 20% of patients even after 48 hours of therapy. The severity and persistence of acidosis was significantly correlated with the stool volume. Our findings indicate that adult patients, with diarrhoea and dehydration are readily rehydrated, if they drink a simple salt-sugar solution. When fluid losses exceed 50 ml/kg/24 hours acidosis will not be corrected for several days. The failure to correct acidosis promptly may not be of great clinical importance in adults with mild diarrhoea, and in such cases sodium bicarbonate may not be needed. More serious consequences of sustained acidosis may result in children and severely affected adults. This requires further evaluation.

UR - http://www.scopus.com/inward/record.url?scp=0018888869&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0018888869&partnerID=8YFLogxK

M3 - Article

C2 - 7365864

AN - SCOPUS:0018888869

VL - 83

SP - 41

EP - 45

JO - Journal of Tropical Medicine and Hygiene

JF - Journal of Tropical Medicine and Hygiene

SN - 0022-5304

IS - 1

ER -