KSTAGE: An interactive computer program for designing phase II clinical trials using predictive probability

E. Neely Atkinson, Barry W. Brown, Jay Herson

Research output: Contribution to journalArticlepeer-review

Abstract

Early termination of clinical trials is advisable if initial evidence indicates the treatment under study is ineffective. Predictive probability methods permit the construction of multistage studies that allow for early termination while still controlling overall false-positive (declare an ineffective treatment effective) and false-negative (declare an effective treatment ineffective) error rates. An interactive computer program known as KSTAGE has been developed that aids the researcher in designing such studies.

Original languageEnglish (US)
Pages (from-to)220-227
Number of pages8
JournalComputers and Biomedical Research
Volume15
Issue number3
DOIs
StatePublished - Jun 1982
Externally publishedYes

ASJC Scopus subject areas

  • Medicine (miscellaneous)

Fingerprint Dive into the research topics of 'KSTAGE: An interactive computer program for designing phase II clinical trials using predictive probability'. Together they form a unique fingerprint.

Cite this