Krüppel-like factors in the vascular endothelium

Guillermo García-Cardeña, Guadalupe Villarreal

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Although Krüppel-like factors (KLFs) have been the subject of extensive biological investigation, the role of this family of transcription factors in the biology and pathophysiology of the vascular endothelium is just becoming apparent. Most investigative efforts thus far have focused on KLF2, its contribution to the endothelial vasoprotective phenotype, and its possible impact on atherogenesis. This chapter reflects on the current state of the field and highlights evolving areas where KLFs are emerging as important regulators of endothelial function.

Original languageEnglish (US)
Title of host publicationThe Biology of Krüppel-like Factors
PublisherSpringer Japan
Pages173-184
Number of pages12
ISBN (Print)9784431877745
DOIs
StatePublished - Dec 1 2009

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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  • Cite this

    García-Cardeña, G., & Villarreal, G. (2009). Krüppel-like factors in the vascular endothelium. In The Biology of Krüppel-like Factors (pp. 173-184). Springer Japan. https://doi.org/10.1007/978-4-431-87775-2-14