Kinetic Vitreous Fluorophotometry in Normals and Noninsulin-Dependent Diabetics

Jose G. Cunha-Vaz, Ran Zeimer, Wendell P. Wong, Reza Kiani

Research output: Contribution to journalArticlepeer-review

Abstract

Kinetic vitreous fluorophotometry was performed up to five hours after intravenous injection of fluorescein in seven normal subjects and seven noninsulin-dependent diabetic patients without retinopathy. The leakage of fluorescein into the vitreous was measured, and fluorescein dynamics were assessed after correction for the most important artifacts. A detailed description of the movements of fluorescein between the blood and the chambers of the eye across the blood-ocular barriers was obtained in normal and diabetic eyes. The diabetic population could be differentiated best from the normal one with vitreous fluorophotometry measurements performed close to the retina-choroid one hour after injection.

Original languageEnglish (US)
Pages (from-to)751-756
Number of pages6
JournalOphthalmology
Volume89
Issue number7
DOIs
StatePublished - 1982

Keywords

  • blood-retinal barrier
  • diabetes
  • fluorophotometry
  • vitreous

ASJC Scopus subject areas

  • Ophthalmology

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