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Kinetic isotope effect studies of the reaction catalyzed by uracil DNA glycosylase: Evidence for an oxocarbenium ion - Uracil anion intermediate
R. M. Werner,
J. T. Stivers
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Article
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peer-review
125
Scopus citations
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Dive into the research topics of 'Kinetic isotope effect studies of the reaction catalyzed by uracil DNA glycosylase: Evidence for an oxocarbenium ion - Uracil anion intermediate'. Together they form a unique fingerprint.
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Medicine & Life Sciences
Uracil-DNA Glycosidase
100%
Deuterium
90%
Uracil
82%
Isotopes
69%
Anions
69%
Ions
53%
Kinetics
46%
Carbon-13
25%
Deoxyribonucleotides
24%
DNA Repair Enzymes
22%
Deoxyuridine
21%
pyrimidine
19%
Carbon
15%
Sugars
15%
DNA Repair
14%
Water
10%
DNA
9%
Chemical Compounds
Kinetic Isotope Effect
70%
Uracil
69%
Transition State Structure
54%
Transition State
52%
Catalysis
41%
Anion
37%
Deoxyribonucleotide
30%
Cleavage
29%
Hyperconjugation
27%
Ion
25%
Dissociation
15%
Carbon Atom
10%