Kidney transplant recipient attitudes toward a sars-cov-2 vaccine

Michael T. Ou, Brian J. Boyarsky, Laura B. Zeiser, Teresa Po Yu Chiang, Jake Ruddy, Sarah E.Van Pilsum Rasmussen, Jennifer Martin, Jennifer St Clair Russell, Christine M. Durand, Robin K. Avery, William A. Werbel, Matthew Cooper, Allan B. Massie, Dorry L. Segev, Jacqueline Garonzik

Research output: Contribution to journalArticlepeer-review

Abstract

Background. A widely accepted severe acute respiratory syndrome 2 (SARS-CoV-2) vaccine could protect vulnerable populations, but the willingness of solid organ transplant recipients (SOTRs) to accept a potential vaccine remains unknown. Methods. We conducted a national survey of 1308 SOTRs and 1617 non-SOTRs between November 11 and December 2, 2020 through the network of the National Kidney Foundation. Results. Respondents were largely White (73.2%), female (61.1%), and college graduates (56.2%). Among SOTRs, half (49.5%) were unsure or would be unwilling to receive a SARS-CoV-2 vaccine once available. Major concerns included potential side effects (85.2%), lack of rigor in the testing and development process (69.7%), and fear of incompatibility with organ transplants (75.4%). Even after the announcement of the high efficacy of the mRNA-1273 vaccine (Moderna Inc.) at the time of survey distribution, likeliness to receive a vaccine only slightly increased (53.5% before announcement versus 57.8% after the announcement). However, 86.8% of SOTRs would accept a vaccine if recommended by a transplant provider. Conclusions. SOTRs reported skepticism in receiving a potential SARS-CoV-2 vaccine, even after announcements of high vaccine efficacy. Reassuringly, transplant providers may be the defining influence in vaccine acceptance and will likely have a critical role to play in promoting vaccine adherence.

Original languageEnglish (US)
Article numbere713
JournalTransplantation Direct
Volume7
Issue number7
DOIs
StatePublished - Apr 2 2021

ASJC Scopus subject areas

  • Transplantation

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