Ketogenic Dietary Therapy Controversies for Its Second Century

Research output: Contribution to journalReview articlepeer-review

Abstract

As the ketogenic diet approaches 100 years of continuous use, we reflect on its successes and consider new avenues of research for the next century. One controversial question is regarding whether ketogenic dietary therapies could be successful first-line treatments for epilepsy. Second, is it possible to mimic the mechanisms of action of ketogenic dietary therapy with a drug (eg, a tablet formulation)? A third controversy worthy of future study involves its expanded usage in adults with refractory epilepsy and its role in treating women of childbearing age. Finally, as flexible, alternative diets have recently become widely available, is it feasible and safe to have families and patients start ketogenic dietary therapy successfully on their own with limited medical supervision?

Original languageEnglish (US)
Pages (from-to)125-129
Number of pages5
JournalEpilepsy Currents
Volume20
Issue number3
DOIs
StatePublished - May 1 2020

Keywords

  • diet
  • epilepsy
  • fasting
  • ketogenic
  • ketosis

ASJC Scopus subject areas

  • Clinical Neurology

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