Abstract
The effect of ketoconazole on the kinetics of antipyrine was investigated. The antipyrine Vd showed an overall difference among the 4 trials, but the magnitude of the differences was small. Antipyrine half-life was slightly but not significantly shortened and the antipyrine clearance was essentially identical in the whole study. The data are commented and interpreted.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 225-226 |
| Number of pages | 2 |
| Journal | International Journal of Clinical Pharmacology Therapy and Toxicology |
| Volume | 24 |
| Issue number | 5 |
| State | Published - 1986 |
| Externally published | Yes |
ASJC Scopus subject areas
- Toxicology
- Pharmacology (medical)