Ketene thioacetal route to γ-lactones. Effect of carbonyl hardness on reaction-site selectivity and a unique preparation of 3-methyl-5-phenyl-2(5H)-furanone

Alan P. Kozikowski, Yon Yih Chen

Research output: Contribution to journalArticle

Abstract

The synthesis of γ-lactones from the addition products of ketene thioacetal anions and carbonyl compounds has been achieved. A unique phenylselenenyl chloride triggered formation of dithienium ion from ketene thioacetal has been shown to directly afford a doubly protected butenolide system.

Original languageEnglish (US)
Pages (from-to)2236-2239
Number of pages4
JournalJournal of Organic Chemistry
Volume45
Issue number11
Publication statusPublished - 1980
Externally publishedYes

    Fingerprint

ASJC Scopus subject areas

  • Organic Chemistry

Cite this