Keratitis caused by candida glabrata in a patient with chronic granulomatous disease

Ali R. Djalilian, Janine A. Smith, Thomas J. Walsh, Harry L. Malech, Michael R. Robinson

Research output: Contribution to journalArticlepeer-review

21 Scopus citations


PURPOSE: To report an unusual ocular presentation of Candida glabrata in a patient with chronic granulomatous disease. METHODS: Interventional case report. A 15-year-old boy with chronic granulomatous disease presented with bilateral limbal infiltrates. He had been receiving broad-spectrum systemic antibiotics for recurrent liver abscesses. The keratitis did not respond to antibiotics and did not resolve after a course of topical steroids. RESULTS: Corneal cultures revealed Candida glabrata. The same species was simultaneously isolated from the surgical drainage of the liver abscesses. The ocular and hepatic findings resolved on intravenous amphotericin B. CONCLUSION: Candida glabrata has recently emerged as an important nosocomial pathogen. It may present as a limbal keratitis in the setting of systemic infection.

Original languageEnglish (US)
Pages (from-to)782-783
Number of pages2
JournalAmerican journal of ophthalmology
Issue number5
StatePublished - 2001

ASJC Scopus subject areas

  • Ophthalmology


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